phenobarbital will increase toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers may perhaps boost the metabolism of ifosfamide to its Energetic alkylating metabolites.Watch Intently (one)somatropin will lower the extent or result of phenobarbital by affecting hepatic/intesti